Efficacy and Safety of Bempedoic Acid in Patients Aged ≥75 Years Stratified by Varying Statin Exposure: Results From Phase 3 Studies of Bempedoic Acid - PubMed
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- #statin therapy
- #elderly patients
- #bempedoic acid
- Bempedoic acid lowers LDL-C effectively in patients aged 75+, with similar placebo-corrected reductions across age groups in both statin-using and statin-intolerant pools.
- Safety profile is generally comparable to placebo across ages, though adverse events were more frequent in patients ≥75 years irrespective of statin background.
- Cardiovascular event reduction with bempedoic acid was statistically similar across all age groups, supporting its use in older adults.