Editor's Note: Small-Molecule NSC59984 Restores p53 Pathway Signaling and Antitumor Effects against Colorectal Cancer via p73 Activation and Degradation of Mutant p53 - PubMed
6 hours ago
- #NSC59984
- #colorectal cancer
- #p53 pathway
- Small-molecule NSC59984 reactivates p53 pathway signaling in colorectal cancer.
- NSC59984 exerts antitumor effects by activating p73 and degrading mutant p53.
- Original study published in Cancer Research in 2015, with an erratum noted.
- The research highlights a potential therapeutic strategy for colorectal cancer targeting mutant p53.