A β-1,3-glucanase antagonizes a phase-separating WRKY repressor to confer saline-alkaline tolerance in rice - PubMed
5 hours ago
- #transcriptional regulation
- #stress tolerance
- #rice
- OsWRKY1 negatively regulates saline-alkaline tolerance in rice; loss enhances tolerance, overexpression increases sensitivity.
- OsWRKY1 undergoes stress-induced liquid-liquid phase separation (LLPS) via an intrinsically disordered region (IDR1), crucial for its repressive function on stress-responsive genes.
- OsGH17, a β-1,3-glucanase, interacts with IDR1 under saline-alkaline stress, reducing OsWRKY1 DNA binding, condensate formation, and transcriptional repression to promote tolerance.