The efficacy of high-flow nasal cannula versus non-invasive mechanical ventilation in preventing reintubation in patients at high risk of extubation failure: systematic review and meta-analysis with t
5 hours ago
- #extubation failure
- #high-flow nasal cannula
- #non-invasive ventilation
- The study compared high-flow nasal cannula (HFNC) and non-invasive ventilation (NIV) in preventing reintubation in high-risk patients.
- No significant differences were found between HFNC and NIV in reintubation rates, ICU or hospital mortality, or length of stay.
- HFNC showed a non-significant trend toward lower post-extubation respiratory failure and ICU mortality in patients ventilated more than 5 days.
- The meta-analysis included 10 randomized controlled trials with 1,697 patients, utilizing trial sequential analysis.
- Primary outcome was reintubation; secondary outcomes included respiratory failure, mortality, and ICU/hospital stay durations.