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Blood Flow Restriction Therapy Stimulates Intercellular Mitochondria Transfer and Improves Muscle Regeneration and Shoulder Function in a Murine Rotator Cuff Injury Model - PubMed

4 days ago
  • #Rotator Cuff Injury
  • #Mitochondrial Transfer
  • #Blood Flow Restriction
  • Blood Flow Restriction (BFR) therapy enhances muscle regeneration and shoulder function in a murine rotator cuff injury model.
  • BFR stimulates intercellular mitochondria transfer from fibro-adipogenic progenitors (FAPs) to myocytes, improving muscle quality.
  • Study shows BFR reduces muscle atrophy, fatty infiltration, and fibrosis post rotator cuff injury.
  • Improved forelimb gait and weightbearing observed in BFR-treated mice at 6 weeks post-injury.
  • Findings suggest BFR could be a novel rehabilitation strategy for rotator cuff injuries and other muscle-related conditions.