The clinical phenotype of anti-Th/To+ patients in systemic sclerosis: a case-control study within the European Scleroderma Trials and Research cohort - PubMed
4 hours ago
- #autoantibodies
- #systemic sclerosis
- #precision medicine
- Study investigates clinical phenotype and outcomes of anti-Th/To+ systemic sclerosis (SSc) patients.
- Anti-Th/To+ patients show lower prevalence of diffuse cutaneous involvement, digital ulcers, and telangiectasias.
- Interstitial lung disease (ILD) and myocarditis are less frequent in anti-Th/To+ patients.
- Anti-Th/To+ patients have milder organ damage and better survival rates compared to controls.
- Findings support the use of autoantibody profiling for personalized SSc management.