ACR Appropriateness Criteria® Demyelinating Diseases - PubMed
5 hours ago
- #ACR Appropriateness Criteria
- #MRI
- #Demyelinating Diseases
- Demyelinating diseases of the central nervous system include multiple sclerosis (MS), neuromyelitis optica spectrum disorders (NMOSD), and myelin oligodendrocyte glycoprotein antibody-associated disorders (MOGAD).
- MRI is the primary imaging modality for detecting demyelinating lesions, with advanced techniques like diffusion tensor imaging and AI applications improving diagnostic accuracy.
- The 2024 McDonald criteria incorporate new imaging features such as the central vein sign and paramagnetic rim lesions, enhancing MS diagnosis accuracy to 94% at 3T MRI.
- Gadolinium enhancement patterns help differentiate active inflammatory lesions from chronic plaques and distinguish MS from NMOSD and MOGAD.
- Spinal cord MRI shows distinct lesion patterns: short peripheral lesions in MS versus longitudinally extensive lesions in NMOSD.
- The American College of Radiology Appropriateness Criteria are evidence-based guidelines reviewed annually by a multidisciplinary expert panel.
- The guideline development process uses methodologies like GRADE and the RAND/UCLA Appropriateness Method to evaluate evidence and determine imaging appropriateness.