Efficacy of torsemide versus furosemide in heart failure: a systematic review and meta-analysis of randomized controlled trials - PubMed
5 hours ago
- #meta-analysis
- #loop diuretics
- #heart failure
- Loop diuretics are central to managing heart failure symptoms, but evidence comparing torsemide and furosemide is conflicting.
- A meta-analysis of 10 RCTs (4011 patients) found no significant difference in all-cause mortality (OR=0.99) or heart failure hospitalization (OR=0.96) between torsemide and furosemide.
- Both diuretics significantly reduced weight (torsemide: mean difference 2.36; furosemide: mean difference 2.48), with no significant difference between them (mean difference -0.15).
- Torsemide and furosemide have similar effects on mortality, hospitalization, and weight change in congestive heart failure patients.