Prospective Associations of Obesity and Obesity Severity With 9 Cardiovascular Outcomes: The Cross-Cohort Collaboration - PubMed
3 months ago
- #cardiovascular disease
- #obesity
- #BMI
- Study examines the relationship between obesity severity and nine cardiovascular outcomes.
- Includes 289,875 participants from 21 cohorts with BMI ≥18.5 kg/m².
- Severe obesity (BMI ≥40 kg/m²) significantly increases risks of heart failure (HR 3.0) and atrial fibrillation (HR 2.8).
- Women with severe obesity have higher relative risks for stroke, CVD, and all-cause mortality compared to men.
- Higher BMI is robustly associated with increased cardiovascular risks, especially heart failure and atrial fibrillation.
- Sex differences suggest potential variations in underlying biological mechanisms.