Staging and imaging-based prognostication in renal cell carcinoma: current guidelines and practical considerations - PubMed
6 hours ago
- #Medical Imaging
- #Renal Cell Carcinoma
- #Prognostication
- Imaging-based staging is crucial for renal cell carcinoma (RCC) management, but anatomic labels alone don't fully capture tumor biology.
- The review compares the use of CT and MRI in RCC staging across major guidelines (American Urological Association, European Association of Urology, National Comprehensive Cancer Network).
- Discusses imaging-based prognostic biomarkers like central non-enhancement, enhancement heterogeneity, diffusion metrics, and radiomic signatures.
- Highlights future directions including advanced technologies (photon counting CT, 89Zr-Girentuximab PET/CT), liquid biopsy integration, and standardized reporting systems (e.g., Kidney Imaging Reporting and Data System).
- Aims to standardize reports and improve decision-making by bridging staging descriptors with prognostic phenotypes.