The effect of perioperative lidocaine during modified radical mastectomy on postoperative pain and immune response: A randomized clinical trial - PubMed
6 hours ago
- #Postoperative Pain
- #Lidocaine
- #Immune Response
- Perioperative lidocaine infusion in modified radical mastectomy patients reduced postoperative pain compared to a control group receiving normal saline.
- Serum interleukin 6 (IL-6) levels 24 hours postoperatively were significantly lower in the lidocaine group, indicating modulation of immune response.
- Lidocaine administration did not show a significant difference in preoperative interleukin 1 beta (IL-1β) levels between groups.
- The study suggests lidocaine's pain control benefits may be linked to reduced pro-inflammatory cytokine production.
- This randomized clinical trial involved 90 women undergoing elective mastectomy under general anesthesia.