Understanding and exploiting superspreading to disrupt Mycobacterium tuberculosis transmission - PubMed
3 days ago
- #superspreading
- #tuberculosis
- #transmission
- The article argues that superspreading, where a few individuals cause most Mycobacterium tuberculosis (Mtb) transmission, is a key, widespread feature of tuberculosis (TB) epidemiology.
- Understanding and targeting superspreading events could lead to strategic interventions with significant impacts on disrupting Mtb transmission and advancing TB elimination efforts.
- Progress toward TB elimination depends on interrupting transmission between infectious individuals and susceptible contacts.
- The authors review historical and contemporary data to support the importance of superspreading in TB.
- Conflicts of interest include funding from the US National Institutes of Health and other organizations, with some authors involved in TB-related trials and boards.