Research advances on the impact of gestational diabetes mellitus on offspring neurodevelopment - PubMed
5 hours ago
- #animal-models
- #gestational-diabetes-mellitus
- #neurodevelopment
- GDM is a common pregnancy complication that can severely impair fetal neurodevelopment, affecting emotional, cognitive, and memory functions.
- The mechanisms of GDM's impact on fetal neural development are not fully understood, partly due to a lack of accurate animal models replicating human GDM features.
- This review evaluates methods for establishing GDM animal models and explores GDM's effects on offspring neurodevelopment and its potential mechanisms.
- It aims to provide a theoretical basis for developing better GDM models, clarifying pathophysiological mechanisms, and exploring new therapies.