Ma Xing Shi Gan Decoction reduces influenza A virus nucleoprotein levels in association with modulation of lactate-HMGB1 lactylation and autophagosome accumulation - PubMed
7 hours ago
- #Autophagy
- #Influenza A Virus
- #Traditional Chinese Medicine
- Ma Xing Shi Gan Decoction (MXSG) reduces influenza A virus nucleoprotein (NP) levels.
- MXSG modulates lactate-HMGB1 lactylation and autophagosome accumulation.
- MXSG alleviates lung inflammatory injury in a mouse model of viral pneumonia.
- MXSG decreases glycolysis-related enzymes and lactate production.
- Buddleoside, a constituent of MXSG, potentially interacts with LDHA.
- MXSG's effects suggest a link between metabolic-autophagy signaling and viral NP reduction.