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Inverse Association Between Composite Dietary Antioxidant Index and Prevalence of Pelvic Inflammatory Disease Among Women: A Cross-Sectional Study of NHANES 2013-2018 - PubMed

4 hours ago
  • #Antioxidants
  • #Pelvic Inflammatory Disease
  • #CDAI
  • Higher composite dietary antioxidant index (CDAI) is associated with lower odds of self-reported history of treated pelvic inflammatory disease (PID) among women.
  • The association was evaluated using survey-weighted multivariable logistic regression and restricted cubic spline analysis, showing an inverse linear trend.
  • Odds ratios for PID across CDAI quartiles (vs. lowest quartile) were: Q2 OR=0.682, Q3 OR=0.524, Q4 OR=0.666.
  • Among CDAI components, vitamin E intake independently showed an inverse association with PID odds.
  • SHAP value interpretation identified vitamin A, vitamin C, and carotenoids as the top predictive contributors within CDAI.
  • Subgroup analysis revealed a significant interaction effect of age on the CDAI-PID association.