Prospective Comparison of 64Copper [64Cu]SAR-bisPSMA vs 68Gallium[68Ga] PSMA-11 PET/CT for Biochemical Recurrence of Prostate Cancer Following Radical Prostatectomy (Co-PSMA Trial) - PubMed
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- #biochemical recurrence
- #PSMA-PET
- #prostate cancer
- 64Cu-bisPSMA detected more lesions per patient (mean 1.26) than 68Ga-PSMA (mean 0.48), with a ratio of 2.63.
- Patient-level positivity was 78% for 64Cu-bisPSMA vs 36% for 68Ga-PSMA, leading to management changes in 44% of cases.
- The reference standard true positive rate was higher for 64Cu-bisPSMA (71%) compared to 68Ga-PSMA (29%).