Joint Assessment of Sarcopenia and Lipid Parameters on Cardiovascular Diseases in Middle-Aged and Older Adults in China With Different Glucose Metabolism Status - PubMed
4 days ago
- #sarcopenia
- #glucose metabolism
- #cardiovascular diseases
- Study investigates joint effect of sarcopenia and lipid parameters on cardiovascular disease (CVD) risk in middle-aged and older Chinese adults with different glucose metabolism statuses.
- Included 9,053 participants from CHARLS 2015 aged ≥45 without baseline CVD, finding 11.9% reported new-onset CVD.
- Sarcopenia combined with elevated lipid parameters (except HDL-C) increased CVD risk, especially in normoglycemic and prediabetic individuals, but not in Type 2 diabetics.
- Non-traditional lipid indices showed modest discriminative ability for CVD risk, with Atherogenic Coefficient having limited but consistent predictive capability across glucose metabolism states.
- Highlights the importance of assessing both sarcopenia and lipid parameters for CVD risk, particularly in individuals with normal glucose regulation and prediabetes.