Nutrition impact symptoms and the risk of malnutrition, frailty, and sarcopenia in adults with cancer: A cross-sectional latent class analysis - PubMed
6 hours ago
- #Malnutrition Risk
- #Symptom Clusters
- #Cancer Nutrition
- Malnutrition, frailty, and sarcopenia are common and interrelated in cancer patients, with prevalences of 56.4%, 37.7%, and 16.9%, respectively, in a study of 28,377 hospitalized adults.
- Weight loss and low muscle mass are key shared features linking malnutrition, frailty, and sarcopenia in cancer patients.
- Five nutrition impact symptom clusters were identified by severity; severe multi-symptom clusters increase odds of malnutrition by 3.87-fold and frailty by 6.03-fold.
- Gastrointestinal-dominant symptom clusters are strongly linked to malnutrition, while sensory-alteration clusters are most associated with frailty.
- Maintaining stable body weight and muscle mass is crucial to reduce comorbidity risks; targeting symptom clusters can improve nutritional care efficiency.