Reactivating p53 mutants selectively in patients - PubMed
5 hours ago
- #mutant reactivation
- #cancer therapy
- #p53
- p53 is the most frequently mutated protein in cancer, inactivated by many different mutations.
- A recent study published in the New England Journal of Medicine reports targeting a common p53 mutant with the reactivator rezatapopt.
- This finding represents an encouraging step toward clinical utility for mutant p53 reactivation therapies.