Bacterial entrapment of a fungal carbon repressor prevents plant colonization - PubMed
7 hours ago
- #microbial consortium
- #Fusarium graminearum
- #carbon catabolite repression
- Bacterial entrapment of a fungal carbon repressor (FgCreA) prevents plant colonization by Fusarium graminearum.
- Pseudomonas CXZ-8 disrupts the nuclear-to-cytoplasmic relocalization of FgCreA, suppressing FCO1 expression crucial for host cell wall degradation and nutrient acquisition.
- This interference benefits the bacterium by preventing harmful host-derived indole derivatives and fungal mycotoxins.
- Approximately 20% of field-isolated bacteria show similar FgCreA-stabilizing activity.
- A microbial consortium enriched for CCR-targeting bacteria conferred broad-spectrum disease resistance in field trials.
- The findings reveal a novel interkingdom interference mode and establish CCR as a conserved microbial vulnerability for sustainable crop protection.