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Global Prevalence of Adherence to Gluten-Free Diet in Patients with Celiac Disease: A Systematic Review and Meta-analysis - PubMed

6 hours ago
  • #celiac disease
  • #gluten-free diet
  • #adherence
  • Strict gluten-free diet (GFD) is the standard treatment for celiac disease (CeD).
  • A systematic review and meta-analysis estimated GFD adherence rates in CeD patients.
  • Pooled adherence prevalence was 64% by objective methods and 74% by self-report.
  • Adherence rates varied by assessment method: 65% (SDE), 57% (CDAT), 75% (BIAGI).
  • Highest adherence rates were found in European and North American countries.
  • No significant difference in adherence rates over time or by participant age.
  • One in three CeD patients fails to maintain good GFD adherence.
  • Strategies to improve GFD adherence are needed.