Prognostic value of the cardiometabolic index for mortality in patients with cardiometabolic syndrome: A longitudinal analysis based on NHANES data - PubMed
4 days ago
- #Cardiometabolic Index
- #NHANES
- #Mortality Risk
- The study evaluates the prognostic value of the Cardiometabolic Index (CMI) for mortality in patients with Cardiometabolic Syndrome (CMS).
- CMI integrates waist-to-height ratio and triglyceride-to-HDL cholesterol ratio, correlating with metabolic dysregulation.
- A cohort of 5476 adult CMS patients from NHANES (1999-2018) was analyzed over a median 95-month follow-up.
- CMI showed a positive association with all-cause mortality (HR = 1.02 per SD increase, P = 0.033).
- A nonlinear link was found between CMI and diabetes-related mortality (HR = 1.07 per unit increase, P = 0.034), with risk surging when CMI exceeded 1.67.
- No significant correlation was observed between CMI and cardiovascular mortality.
- Subgroup analysis confirmed enhanced CMI predictive performance in high-risk populations.
- Sensitivity analyses verified the robustness of the findings.
- CMI serves as a novel biomarker for all-cause and diabetes-related mortality risk in CMS patients, supporting risk stratification.