AMPK as a regulatory node in cell death - PubMed
5 hours ago
- #cell death
- #AMPK
- #therapeutic potential
- AMPK is a critical kinase in cellular metabolism regulation.
- AMPK plays a key role in regulating various types of regulated cell death (RCD) pathways, including apoptosis, necroptosis, pyroptosis, and ferroptosis.
- The review discusses AMPK's regulatory roles in different RCD forms.
- AMPK's implications in diseases like cancer, diabetes complications, ischemia-reperfusion injury, and infectious diseases are examined.
- The therapeutic potential of AMPK activators and inhibitors through RCD regulation is highlighted.