Human skin DNA fertilised to make embryo for first time
10 hours ago
- #genetics
- #reproductive-technology
- #fertility
- US scientists created early-stage human embryos using DNA from skin cells fertilized with sperm.
- The technique could help overcome infertility due to age or disease and enable same-sex couples to have genetically related children.
- The method requires refinement and could take a decade before clinical use.
- The process involves transferring a skin cell nucleus into a donor egg stripped of its genetic material.
- The egg undergoes 'mitomeiosis' to discard half its chromosomes, but the process is not yet precise.
- The study achieved an 82-egg success rate, with some progressing to early embryo stages, but none beyond six days.
- The technique is part of in vitro gametogenesis, aiming to create sperm and eggs outside the body.
- Potential applications include helping older women, men with low sperm counts, and cancer survivors regain fertility.
- Experts emphasize the need for public dialogue, governance, and safety before clinical adoption.