Astroglial and Neuronal Injury Markers (GFAP, UCHL-1, NfL, Tau, S100B) as Diagnostic and Prognostic Biomarkers in PTSD and Neurological Disorders - PubMed
6 hours ago
- #biomarkers
- #PTSD
- #neuroinflammation
- PTSD involves neuroinflammation, glial dysfunction, and neuronal injury.
- Chronic stress leads to BBB disruption, oxidative stress, and neural damage.
- Biomarkers like GFAP, UCHL-1, NfL, Tau, and S100B indicate brain dysfunction in PTSD.
- GFAP and S100B reflect astrocyte activation and BBB permeability.
- UCHL-1, NfL, and Tau indicate neuronal injury and axonal degeneration.
- Altered biomarker levels correlate with symptom severity and cognitive impairment in PTSD.
- These biomarkers may aid in early diagnosis and personalized treatment strategies.