Long-term thrombus-free left atrial appendage occlusion via magnetofluids - PubMed
4 hours ago
- #cardiology
- #medical innovation
- #biomaterials
- Proposes a personalized and complete left atrial appendage occlusion (LAAO) using magnetofluids suitable for all LAA types.
- Magnetofluids can be injected via cardiac catheters, resist high-speed blood flow under a magnetic field, and precipitate into magnetogels within minutes.
- Demonstrated long-term resilience and biocompatibility of magnetogel over 10 months in a pig model with no thrombus or leakage observed.
- Comparison with Watchman occluder showed magnetogel's smooth, firm, thrombus-free endocardium formation without myocardial injury.
- Offers a promising clinical strategy for thrombus-free LAAO without the drawbacks of current solid occluders.