Transmission dynamics of Oropouche virus in Latin America and the Caribbean - PubMed
8 hours ago
- #Oropouche virus
- #Latin America
- #epidemiology
- Oropouche virus (OROV) re-emerged in late 2023, causing a major epidemic across Central and South America.
- In Manaus City, Brazil, OROV IgG seroprevalence increased from 11.4% in November 2023 to 25.7% in November 2024.
- Neutralizing antibodies from individuals showed high titers against both historical and contemporary OROV isolates.
- Historical reconstruction in Manaus indicated continuous low-level transmission with major outbreaks in 1980-1981 and 2023-2024.
- Estimated OROV infections: ~336,000 in the Amazon under endemic transmission and over 9.4 million during major outbreaks from 1960 to 2025.