Dehydration promotes intracellular lipid synthesis and accumulation - PubMed
4 hours ago
- #mitochondrial metabolism
- #lipid synthesis
- #dehydration
- Dehydration and hypertonic stress lead to decreased oxygen consumption in cells.
- This stress increases intracellular lipid synthesis and accumulation.
- Mitochondrial metabolism is remodeled, favoring glutamine oxidation as a carbon source for lipid production.
- Lipids act as a water reservoir, offsetting dehydration through mitochondrial oxidation.
- The findings link water availability directly to lipid storage mechanisms.