ALDH2 Mediated Ferroptosis Regulation in Ischemia-Reperfusion Injury - PubMed
5 hours ago
- #ischemia-reperfusion injury
- #ALDH2
- #ferroptosis
- ALDH2 is an important protective enzyme against ischemia-reperfusion injury (IRI).
- Ferroptosis is a key cell death pathway in IRI driven by iron and lipid peroxidation.
- ALDH2 and ferroptosis intersect, with ALDH2 limiting toxic lipid peroxidation products.
- Targeting ALDH2 may be a strategy to reduce ferroptosis and tissue damage in IRI.