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The Care and Cure of the Leukemias in 2026 - PubMed

5 hours ago
  • #immunotherapy
  • #leukemia
  • #targeted therapy
  • Development of novel targeted therapies and advances in genomics have transformed leukemia treatment.
  • Immunotherapies, TKIs, BCL-2 inhibitors, and CAR T-cell therapies have significantly improved survival rates.
  • Philadelphia-positive ALL and CLL, once incurable, now have high 5- and 10-year survival rates.
  • BCR::ABL1 TKIs have enabled normal life expectancy in chronic myeloid leukemia.
  • Targeted therapies have advanced AML treatment, though some subsets still face poor outcomes.
  • The optimistic view is that most, if not all, leukemias are curable with current and emerging therapies.