MR Elastography Characterization of Biomechanical Properties to Enhance Enterographic Fibrosis Diagnosis - PubMed
4 hours ago
- #MR Elastography
- #Crohn's Disease
- #Fibrosis Diagnosis
- MR elastography evaluates biomechanical properties to improve Crohn's disease fibrosis diagnosis.
- Study includes 56 participants with CD undergoing MR elastography and enterography.
- Shear-wave speed (SWS) and loss angle (φ) correlate with fibrosis severity and collagen proportion.
- Piezo1 expression serves as a stiffness reference, correlating with fibrosis markers.
- XGBoost algorithm outperforms others, with elastography enhancing diagnostic accuracy (AUC 0.89).
- MR elastography adds significant value to conventional MR enterography for fibrosis assessment.