Frequency of AQP4 and MOG Antibodies in Patients With Optic Neuritis Fulfilling Minimal New Multiple Sclerosis MRI Criteria - PubMed
5 hours ago
- #MRI Criteria
- #Optic Neuritis
- #Multiple Sclerosis
- Study assesses frequency of non-MS diagnoses in patients with optic neuritis (ON) and minimal MS MRI criteria.
- 96 patients analyzed: 76% diagnosed with MS, 24% with MOG antibody-associated disease or neuromyelitis optica spectrum disorder.
- Longitudinally extensive lesions, bilateral involvement, chiasmal enhancement, or optic perineuritis were observed in all non-MS patients and 24.6% of MS patients.
- Recommendations include AQP4 and MOG antibody testing and careful orbital MRI interpretation for ON patients meeting minimal MS criteria.