A gut microbiome-kidney-heart axis predictive of future cardiovascular diseases - PubMed
3 days ago
- #cardiovascular disease
- #metabolites
- #gut microbiome
- The study identifies a gut microbiome-kidney-heart axis that predicts future cardiovascular diseases (CVD).
- Gut microbiome-related changes are linked to subclinical variations in heart and kidney function.
- Markers related to gut microbial metabolism of aromatic amino acids (phenylalanine and tyrosine) associate with pro-atrial natriuretic peptide and estimated glomerular filtration rate.
- Microbiome-related metabolites act as mediators in the gut microbiome-kidney axis, with baseline levels associated with incident CVD in an external population.
- The research suggests the gut microbiome interacts with the cardiorenal axis, influencing host physiology and CVD risk.