Blood Inflammation Indexes Mediate the Association Between Weight-Adjusted-Waist Index and Cognitive Function Among Older Adults in the United States - PubMed
4 hours ago
- #cognitive function
- #blood inflammation
- #weight-adjusted-waist index
- Higher weight-adjusted-waist index (WWI) correlates with lower cognitive performance in older adults, specifically in verbal learning and processing speed tasks.
- WWI shows a positive association with blood inflammation indexes such as SIRI, SII, and NLR.
- Blood inflammation indexes (SIRI and NLR) partially mediate the negative relationship between WWI and cognitive function.
- The study used NHANES data from 2011-2014 and assessed cognition using CERAD tests, Animal Fluency, and Digit Symbol Substitution.
- Mediation analysis suggests inflammation may be a pathway linking central obesity (measured by WWI) to cognitive decline.