Early detection of gastric cancer: a novel circulating microbiome DNA based liquid biopsy assay - PubMed
4 hours ago
- #Liquid Biopsy
- #Machine Learning
- #Gastric Cancer Detection
- This study developed a machine learning diagnostic model called cmDNA-MLM for detecting gastric cancer using circulating microbiome DNA.
- The model achieved high accuracy, with AUC values of 0.831 in the testing cohort and 0.914 in an independent validation cohort.
- It demonstrated strong performance in early-stage detection, achieving an AUC of 0.792 for stage I gastric cancer.