Association of the Planetary Health Diet with dementia risk and brain pathology - PubMed
21 hours ago
- #Brain Pathology
- #Planetary Health Diet
- #Dementia Risk
- High adherence to the Planetary Health Diet (PHD) was associated with a lower risk of all-cause dementia (HR=0.71) and Alzheimer's dementia (HR=0.70) over a median 7.5-year follow-up.
- High PHD adherence led to reduced Alzheimer's disease brain pathologies and delayed dementia onset by approximately 2.17 years.
- Participants with high PHD adherence showed better cognitive function proximate to death compared to those with lower adherence.
- The study involved 926 dementia-free adults (mean age 79.4) followed for up to 20 years, with dietary adherence assessed via a food-frequency questionnaire.
- Brain autopsies in 581 decedents quantified Alzheimer's disease, vascular, and other pathologies, linking dietary patterns to brain health outcomes.