The joint association of the combined triglyceride-glucose index and atherogenic index of plasma with hypertension on stroke risk across different glycemic status: a prospective cohort study - PubMed
6 hours ago
- #stroke risk
- #hypertension
- #TyG-AIP
- Higher TyG-AIP (product of triglyceride-glucose index and atherogenic index of plasma) is independently associated with increased stroke risk, with stronger effect in dysglycemic individuals.
- A synergistic interaction exists between TyG-AIP and hypertension; combined high TyG-AIP and hypertension confers the greatest stroke risk (HR=2.89).
- The 'high-and-declining' TyG-AIP trajectory showed highest stroke risk in dysglycemia group, and combining TyG-AIP with hypertension improved risk prediction (AUC=0.643) over hypertension alone.