Investigating the mechanistic link between pesticide DDT and breast cancer through network toxicology, molecular docking, and molecular dynamics simulation - PubMed
5 hours ago
- #Molecular Docking
- #DDT
- #Breast Cancer
- Study investigates the link between pesticide DDT and breast cancer using network toxicology, molecular docking, and molecular dynamics simulation.
- Identified 12 DDT-associated breast cancer targets, including AR, ESR1, ESR2, and ERBB2, involved in hormone and growth factor signaling pathways.
- Highlights the need for further epidemiological and clinical studies to understand DDT's impact on breast cancer risk.
- Data sourced from publicly available databases like TCGA and GEO, ensuring no ethical concerns.
- Findings could inform future prevention and treatment strategies related to DDT exposure and breast cancer.