Effect of Ultra-Processed Foods Consumption on Human Health Outcomes: An Umbrella Review of Systematic Reviews and Meta-Analyses - PubMed

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UPFs are industrial formulations high in sugar and saturated fats, linked to negative health effects.
High UPF consumption is associated with increased risks of adiposity, respiratory diseases, and obesity in children and adolescents.
In adults, higher UPF intake correlates with increased risk of all-cause mortality, type 2 diabetes, mental and sleep disorders, cardiovascular and digestive diseases, and various cancers, with gender-specific risks.
Limited inverse associations were found, such as certain cereals and dairy foods linked to reduced risk of hypertension, adiposity, and lipid profile issues.
Of the 26 studies reviewed, 16 were rated as good quality, 7 as acceptable, and 3 as poor.
UPF consumption is primarily associated with higher risks of chronic noncommunicable diseases, mortality, and mental disorders, but evidence strength varies, requiring cautious interpretation.

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