Liposomal Bupivacaine versus Ropivacaine with Dexamethasone in Rectus Sheath Block for Laparoscopic Gastrectomy: A Randomized Controlled Trial - PubMed
6 hours ago
- #regional anesthesia
- #postoperative analgesia
- #opioid reduction
- Study compared liposomal bupivacaine (LB) and ropivacaine-dexamethasone (RD) in rectus sheath blocks for laparoscopic gastrectomy.
- LB groups (with or without dexamethasone) showed lower opioid use and pain scores than RD group up to 48 hours post-surgery.
- No significant difference found between LB alone and LB with dexamethasone (LBD), indicating dexamethasone added no extra benefit.
- LB groups had lower inflammatory markers (IL-1β, IL-6) at 24h and better recovery scores (QoR-15) than RD group.
- No differences in hospital stay, PACU duration, or satisfaction among groups; LB reduced PONV rates compared to RD.
- Conclusion: LB provides superior analgesia and reduces opioid need vs. RD, but dexamethasone addition offers no further advantage.