Effects of socioeconomic status on adverse pregnancy outcomes: a Mendelian randomisation and mediation analysis - PubMed
6 hours ago
- #Mendelian randomization
- #socioeconomic status
- #pregnancy outcomes
- Higher educational level was found to be causally linked to reduced risks of several adverse pregnancy outcomes, including gestational diabetes, gestational hypertension, and pre-eclampsia.
- Body mass index (BMI) mediated a significant portion (50.8-60.3%) of the associations between education level and gestational diabetes, gestational hypertension, and pre-eclampsia.
- Cigarette consumption mediated 28.1% of the association with ectopic pregnancy, and alcohol intake frequency explained 42.1% of the link with gestational hypertension.
- The study used Mendelian randomization to establish causal relationships, suggesting socioeconomic disadvantage, particularly lower education, directly impacts pregnancy outcomes through modifiable factors.