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Transcatheter aortic valve thrombosis - PubMed

6 hours ago
  • #valve thrombosis
  • #antithrombotic therapy
  • #TAVI
  • Transcatheter aortic valve implantation (TAVI) is increasingly used in younger and lower-risk patients, raising concerns about valve thrombosis.
  • Valve thrombosis in TAVI prostheses can lead to bioprosthetic valve dysfunction and thromboembolic events.
  • Detection of valve thrombosis is challenged by differences in sensitivity and heterogeneity among imaging modalities.
  • Long-term implications of valve thrombosis, including stroke risk and prosthesis longevity, remain uncertain.
  • Current treatment options include anticoagulation therapy, thrombolysis, and reintervention in some cases.
  • Ongoing research focuses on improving detection and treatment through standardized imaging protocols and antithrombotic regimens.
  • Prevention requires better understanding of patient- and procedure-related risk factors to individualize therapy and improve prosthesis design.
  • The review outlines mechanisms, prevalence, clinical relevance, and management of TAVI thrombosis, highlighting ongoing clinical trials.