Higher Grip Strength Is Associated With Reduced Risk of Incident Symptomatic Hand Osteoarthritis: Data From Two Cohort Studies - PubMed
9 hours ago
- #hand osteoarthritis
- #grip strength
- #Mendelian randomization
- Higher grip strength is linked to a reduced risk of developing symptomatic hand osteoarthritis (HOA) based on data from two cohort studies.
- The study used data from the Xiangya Osteoarthritis Study and UK Biobank, including Mendelian randomization analyses to assess causality.
- Results showed that each quartile increase in grip strength significantly lowered the odds of symptomatic HOA, with a clear dose-response trend.
- Mendelian randomization supported a causal relationship, indicating genetically determined higher grip strength reduces HOA risk.
- The findings suggest that interventions to enhance grip strength could help prevent symptomatic HOA and alleviate its burden.