Effects of Baduanjin combined with cognitive training in older adults with mild cognitive impairment of mixed etiologies: a study protocol for a randomized controlled trial - PubMed
4 hours ago
- #Mild Cognitive Impairment
- #Randomized Controlled Trial
- #Baduanjin
- Study protocol for a randomized controlled trial (RCT) on effects of Baduanjin combined with cognitive training in older adults with mild cognitive impairment (MCI).
- Aims to enroll 186 participants for 12 weeks to compare sequential Baduanjin exercise followed by cognitive training, Baduanjin alone, and cognitive training alone.
- Primary outcomes include global cognitive function assessed by MoCA and neurophysiological changes measured with fNIRS in prefrontal, premotor, and supplementary motor cortices.
- Secondary outcomes include specific cognitive domains, balance, activities of daily living, resting heart rate, and heart rate variability.
- Seeks to elucidate neurophysiological mechanisms through fNIRS-derived brain activation and connectivity, providing evidence for non-pharmacological MCI interventions.