National and subnational burden of XDR-TB in China,1990-2023: Long-term trends, regional disparities, and projections, 2024-2050 - PubMed
6 hours ago
- #XDR-TB
- #Disease Burden
- #Epidemiology
- China faces a significant burden of extensively drug-resistant tuberculosis (XDR-TB), with rising prevalence despite overall TB decline.
- From 1990 to 2023, XDR-TB indicators such as incidence, prevalence, and mortality rates showed increasing trends across all 33 administrative regions in China.
- Xinjiang and Tibet are the most affected regions, with Xinjiang leading in incidence, prevalence, and deaths, while Tibet has the highest mortality rates.
- Western regions, including Hong Kong, Macao, Tibet, and Xinjiang, experienced the largest increases in age-standardized rates (ASR).
- The study highlights the need for targeted interventions in high-risk areas and enhanced prevention measures for the elderly to reduce the XDR-TB burden.