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Researchers uncover molecular connection between body fat and anxiety

a year ago
  • #metabolism
  • #anxiety
  • #mental health
  • Researchers at McMaster University discovered a novel link between body fat and anxiety.
  • Psychological stress triggers lipolysis in fat cells, releasing fats that stimulate the hormone GDF15 from immune cells in fat tissue.
  • GDF15 communicates with the brain, leading to anxiety, as shown in experiments with mice.
  • The findings suggest potential new treatments for anxiety by targeting metabolic pathways, including GDF15 blockers.
  • The study was published in Nature Metabolism and funded by CIHR and Diabetes Canada.