Systemic Inflammation Markers in Migraine: A Cross-Sectional Study - PubMed
5 hours ago
- #migraine
- #inflammation
- #immune-dysregulation
- The study explores systemic immune alterations in migraine patients using complete blood count (CBC) parameters and derived inflammatory indices.
- Findings show significant differences in systemic immune-inflammation index (SII) and neutrophil percentages between chronic migraine (CM) patients and healthy controls (HCs).
- Chronic migraine (CM) patients exhibited higher SII and neutrophil% compared to episodic migraine (EM) patients and HCs.
- Lymphocyte percentages were lower in CM patients compared to HCs, indicating systemic immune dysregulation in migraine.
- The study suggests that simple blood-derived markers could help identify inflammatory endophenotypes in migraine, warranting further validation in larger studies.