Traditional Chinese medicine and formulations for the treatment of colorectal cancer: Preclinical studies based on the concept of strengthening the body and eliminating pathogens - PubMed
12 hours ago
- #Fuzheng Quxie
- #Colorectal Cancer
- #Traditional Chinese Medicine
- Traditional Chinese medicine (TCM) is gaining attention for treating colorectal cancer (CRC) based on the concept of 'Strengthening the Body and Eliminating Pathogens' (Fuzheng Quxie).
- CRC pathogenesis in TCM theory involves deficiency of vital energy (Zheng Qi) and invasion of pathogenic factors (Xie Qi), requiring restoration of yin-yang balance.
- Four TCM syndromes of CRC are identified: spleen deficiency with dampness obstruction, damp-heat accumulation, blood stasis and toxin obstruction, and Qi and blood deficiency.
- Commonly used TCM herbs include Atractylodes macrocephala, Poria cocos, Pulsatilla chinensis, and Hedyotis diffusa, along with formulations like Si Jun Zi Tang and Bai Tou Weng Tang.
- The study provides insights into TCM therapeutic mechanisms for CRC and guidance for future preventive strategies and clinical practice.