Duration-Dependent Efficacy and Clinical Safety of Repeated Low-Level Red-Light Therapy for Paediatric Myopia: A Systematic Review and Meta-Analysis - PubMed
5 hours ago
- #meta-analysis
- #red-light therapy
- #paediatric myopia
- Repeated low-level red-light (RLRL) therapy is a non-invasive intervention for controlling paediatric myopia progression.
- The study evaluated RLRL's efficacy and safety based on randomised controlled trials (RCTs).
- RLRL therapy showed duration-dependent myopia control, with improvements in spherical equivalent refraction (SER), axial length (AL), and choroidal thickness (ChT).
- Greater efficacy was observed in children with higher baseline myopia.
- Uncorrected visual acuity (UCVA) was higher with RLRL therapy, while anterior chamber depth (ACD), central corneal thickness (CCT), and lens thickness (LT) remained unchanged.
- Adverse events were mild and transient, with no consistent structural or functional abnormalities.
- Moderate-certainty evidence supports improvement in SER and ChT, but evidence for AL remains of lower certainty.
- Longer-term trials with comprehensive retinal safety assessment are needed.