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Cardiopulmonary exercise testing in contemporary cardiology: physiological insights, novel applications and evolving algorithms - PubMed

5 hours ago
  • #Heart Failure
  • #Exercise Testing
  • #Cardiology
  • Cardiopulmonary exercise testing (CPET) assesses exercise intolerance by evaluating pulmonary, cardiovascular, muscular, and cellular oxidative systems.
  • CPET is standard for diagnosing exercise intolerance, especially in heart failure and hypertrophic cardiomyopathy.
  • Invasive CPET (iCPET) is increasingly used for diagnosing heart failure with preserved ejection fraction (HFpEF) and exercise-induced pulmonary hypertension.
  • Combining CPET with echocardiography (CPET imaging) provides additional insights into atrial and biventricular valve function, though less accurate for hemodynamic assessment.
  • New algorithms are being developed to categorize unexplained dyspnoea in HFpEF, beyond traditional gas exchange classifications.
  • Advancements include wearable systems and artificial intelligence for estimating peak oxygen consumption.
  • This review highlights modern applications and future perspectives of CPET in cardiology.